| All Time Matchup | BUF - 2 || SEA - 5 || 0 ties Last Game: Week 21, 1989 - Seattle Seahawks - 27 @ Buffalo Bills - 31 | | Record | 9-7-0 (3-4-0 Away) |
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| Coach | Marv Levy |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D43 |
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| Offense | Overall - 6191(7) : Pass - 4083(10) : Rush - 2108(12) |
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| Defense | Overall - 5787(8) : Pass - 4479(20) : Rush - 1308(1) |
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| Leading Passer | Mike Ngo - 3322 |
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| Leading Rusher | Greg Bell - 1430 |
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| Leading Receiver | Marvin Harrison - 1299 |
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| Leading Tackler | Mike Singletary - 124 |
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| Turnovers | 21 Take Aways / 17 Turn Overs (+4) |
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| Penalties | 101 For 829 Yards |
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| | Record | 6-10-0 (4-3-0 Home) |
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| Coach | Johnny Mnemonic |
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| Off Scheme | WestCoastHybrid |
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| Def Scheme | D34Hybrid |
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| Offense | Overall - 5364(15) : Pass - 2921(17) : Rush - 2443(4) |
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| Defense | Overall - 6458(17) : Pass - 4285(18) : Rush - 2173(13) |
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| Leading Passer | Randall Cunningham - 1699 |
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| Leading Rusher | Forrest Gump - 879 |
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| Leading Receiver | Art Monk - 724 |
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| Leading Tackler | Bryan Cox - 116 |
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| Turnovers | 18 Take Aways / 14 Turn Overs (+4) |
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| Penalties | 100 For 806 Yards |
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| Last Game Starters |
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Buffalo Bills Offense| Quarterback | Mike Ngo |
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| Running Backs | Greg Bell - Tuffy Leemans |
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| Receivers | Marvin Harrison - Andre Reed |
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| Tight End | Pete Metzelaars |
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| Offensive Line | Anthony Munoz - Jahri Evans - Nick Mangold - Cam Jurgens - Eric Young |
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Buffalo Bills Defense
| Defensive Line | Reggie White - Russell Maryland - Darryl Grant - Simeon Rice |
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| Linebackers | Pat Swilling - Mike Singletary - Lawrence Taylor |
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| Cornerbacks | Everson Walls - Marcus Jones CB |
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| Safeties | Eugene Robinson - Nick Cross |
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| Kicker / Punter | Nick Novak - Jake Camarda |
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| Seattle Seahawks Offense| Quarterback | Randall Cunningham |
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| Running Backs | Forrest Gump - Matt Suhey |
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| Receivers | Art Monk - Cris Collinsworth |
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| Tight End | Jay Novacek |
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| Offensive Line | Lance Smith - Dan Fike - Don Mosebar - Marshal Yanda - Lance Smith |
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Seattle Seahawks Defense
| Defensive Line | Elvis Dumervil - Ted Washington - Mario Williams |
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| Linebackers | Pepper Johnson - Bryan Cox - Clay Matthews - Tamba Hali |
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| Cornerbacks | Trent McDuffie - Wendell Cason |
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| Safeties | Wes Hopkins - Donte Whitner |
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| Kicker / Punter | John Kasay - Sean Landeta |
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| Injuries |
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Buffalo Bills Injuries
| Andre Reed (WR) | Jammed Toe (Questionable) |
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| Simeon Rice (DE) | Jammed Finger (Probable) |
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| Seattle Seahawks Injuries
| Art Monk (WR) | Fractured Cheekbone (Probable) |
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| LaRon Landry (FS) | Fractured Leg (Out for the season) |
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| Herman Edwards II (CB) | Torn Miniscus (Doubtful) |
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