| All Time Matchup | SF - 2 || NYG - 0 || 0 ties
Last Game: | | Record | 9-7-0 (3-5-0 Away) |
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| Coach | Grace Savage |
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| Off Scheme | WestCoastHybrid |
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| Def Scheme | D34 |
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| Offense | Overall - 5832(12) : Pass - 3367(11) : Rush - 2465(3) |
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| Defense | Overall - 5838(11) : Pass - 3190(3) : Rush - 2648(19) |
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| Leading Passer | Brock Purdy - 2545 |
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| Leading Rusher | Joe Perry - 1153 |
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| Leading Receiver | Anthony Carter - 869 |
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| Leading Tackler | Dennis Smith - 110 |
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| Turnovers | 18 Take Aways / 15 Turn Overs (+3) |
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| Penalties | 90 For 812 Yards |
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| | Record | 13-3-0 (6-2-0 Home) |
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| Coach | Clayton Bigsby |
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| Off Scheme | WestCoast |
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| Def Scheme | D34Hybrid |
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| Offense | Overall - 6757(3) : Pass - 4994(2) : Rush - 1763(16) |
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| Defense | Overall - 5052(2) : Pass - 3388(6) : Rush - 1664(3) |
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| Leading Passer | Jay Cutler - 4994 |
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| Leading Rusher | Reggie Bush - 1208 |
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| Leading Receiver | Al Toon - 1334 |
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| Leading Tackler | Zach Thomas - 159 |
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| Turnovers | 42 Take Aways / 22 Turn Overs (+20) |
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| Penalties | 100 For 781 Yards |
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| Last Game Starters |
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San Francisco 49ers Offense| Quarterback | Brock Purdy |
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| Running Backs | Joe Perry - Mike Rozier |
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| Receivers | Anthony Carter - Jerry Rice |
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| Tight End | Steve Jordan |
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| Offensive Line | Willie Anderson - Mike Munchak - Steve McKinney - Chris Chester - Joe Jacoby |
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San Francisco 49ers Defense
| Defensive Line | Charles Mann - John Jurkovic - Jacob Green |
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| Linebackers | Johnny Rembert - Nik Bonitto - Gary Plummer - Freddie Joe Nunn |
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| Cornerbacks | Frank Minnifield - Ray Horton |
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| Safeties | Reed Blankenship - Dennis Smith |
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| Kicker / Punter | Scott Blanton - Jon Ryan |
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New York Giants Offense| Quarterback | Jay Cutler |
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| Running Backs | Reggie Bush - Kevin Mack |
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| Receivers | Al Toon - Mark Clayton |
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| Tight End | Mark Bavaro |
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| Offensive Line | Lomas Brown - Mike Wahle - Jeff Hartings - Ed Ingram - Eric Winston |
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New York Giants Defense
| Defensive Line | Howie Long - Dave Butz II - Chuck Howley |
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| Linebackers | Kevin Greene - Zach Thomas - DeMeco Ryans - Rickey Jackson |
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| Cornerbacks | Larry Brown - Lemar Parrish |
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| Safeties | Harry Hamilton - Gill Byrd |
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| Kicker / Punter | John Lee - Joe Prokop |
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| Injuries |
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San Francisco 49ers Injuries
| Freddie Joe Nunn (LB) | Pulled Hamstring (Probable) |
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| James Williams (T) | Torn Biceps Muscle (Questionable) |
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| Tim McKyer (CB) | Sprained Ankle (Out (2-4 weeks)) |
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New York Giants Injuries
| Gill Byrd (SS) | Sprained Wrist (Probable) |
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| Al Toon (WR) | Dislocated Shoulder (Doubtful) |
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| Muhsin Muhammad (WR) | Patella Tendinitis (Probable) |
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| Ed Ingram (G) | Migraine (Probable) |
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