| All Time Matchup | BUF - 2 || NYG - 3 || 0 ties
Last Game: Week 10, 1986 - Buffalo Bills - 6 @ New York Giants - 17 | | Record | 3-2-0 (2-1-0 Away) |
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| Coach | Marv Levy |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D43 |
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| Offense | Overall - 6707(6) : Pass - 4477(10) : Rush - 2230(12) |
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| Defense | Overall - 6264(12) : Pass - 4703(20) : Rush - 1561(1) |
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| Leading Passer | Mike Ngo - 3322 |
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| Leading Rusher | Greg Bell - 1494 |
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| Leading Receiver | Marvin Harrison - 1299 |
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| Leading Tackler | Mike Singletary - 124 |
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| Turnovers | 24 Take Aways / 17 Turn Overs (+7) |
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| Penalties | 115 For 949 Yards |
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| | Record | 2-3-0 (1-1-0 Home) |
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| Coach | Clayton Bigsby |
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| Off Scheme | WestCoast |
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| Def Scheme | D34Hybrid |
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| Offense | Overall - 7293(2) : Pass - 5377(2) : Rush - 1916(16) |
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| Defense | Overall - 5379(2) : Pass - 3520(2) : Rush - 1859(4) |
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| Leading Passer | Jay Cutler - 5377 |
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| Leading Rusher | Reggie Bush - 1309 |
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| Leading Receiver | Al Toon - 1334 |
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| Leading Tackler | Zach Thomas - 170 |
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| Turnovers | 43 Take Aways / 22 Turn Overs (+21) |
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| Penalties | 103 For 799 Yards |
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| Last Game Starters |
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Buffalo Bills Offense| Quarterback | Mike Ngo |
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| Running Backs | Joseph Addai - Tuffy Leemans |
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| Receivers | Andre Reed - Sidney Rice |
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| Tight End | Pete Metzelaars |
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| Offensive Line | Anthony Munoz - Jahri Evans - Nick Mangold - Cam Jurgens - Winston Justice |
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Buffalo Bills Defense
| Defensive Line | Frostee Rucker - Russell Maryland - Tony Casillas - Reggie White |
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| Linebackers | Pat Swilling - Mike Singletary - Lawrence Taylor |
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| Cornerbacks | Sauce Gardner - Kaiir Elam |
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| Safeties | Eugene Robinson - Rodney Harrison |
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| Kicker / Punter | Nick Novak - Jake Camarda |
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New York Giants Offense| Quarterback | Jay Cutler |
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| Running Backs | Reggie Bush - Kevin Mack |
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| Receivers | Al Toon - Herman Moore |
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| Tight End | Jeremy Ruckert |
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| Offensive Line | Lomas Brown - Mike Wahle - Jeff Hartings - Jim Sweeney - Eric Winston |
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New York Giants Defense
| Defensive Line | Howie Long - Dave Butz II - Chuck Howley |
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| Linebackers | Kevin Greene - Zach Thomas - DeMeco Ryans - Rickey Jackson |
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| Cornerbacks | Lemar Parrish - Larry Brown |
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| Safeties | Harry Hamilton - Gill Byrd |
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| Kicker / Punter | Ray Finkle - Joe Prokop |
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| Injuries |
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Buffalo Bills Injuries
| Nick Mangold (C) | Patella Tendinitis (Questionable) |
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| London Fletcher (LB) | Deep Thigh Bruise (Questionable) |
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New York Giants Injuries
| Gill Byrd (SS) | Bruised Jaw (Probable) |
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| Al Toon (WR) | Bruised Hip (Probable) |
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| Larry Brown (CB) | Fatigue (Probable) |
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| Derion Kendrick (CB) | Hernia (Probable) |
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| Chuck Howley (DE) | Bruised Hip (Probable) |
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